Recombinant Mouse Hepcidin/Hepc protein (TRX, His tag)
Product Specifications
Background
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
Abbreviation
Hepcidin; Hepc
Synonyms
HEPC_MOUSE; Hamp; Hamp1; Hepc; Hepc1; Hepcidin
UniProt
Q9EQ21
Accession Number
Q9EQ21
Expression System
E.coli
Tag
N-Trx-His
Sequence
Asp59-Thr83
Field of Research
Immunology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/dupzhc
Product MSDS
https://789.bio/eb/te1OGG
Calculated Molecular Weight
22.6 kDa
Observed Molecular Weight
25 kDa
Species
Mouse
Available Sizes
Curated Selection
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