Recombinant Mouse CD74 protein (His Tag)
Product Specifications
Background
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.
Abbreviation
CD74
Synonyms
CD 74; CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex; CD74 molecule; CLIP; DHLAG; Gamma chain of class II antigens; HG2A; HLA class; class II antigen-associated) ; class II invariant chain; major histocompatibility complex
UniProt
P04441
Accession Number
P04441
Expression System
E.coli
Tag
N-His & C-His
Sequence
Gln56-Leu279
Applications
Immunogen
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
25.3 kDa
Observed Molecular Weight
26-32 kDa
Species
Mouse
Available Sizes
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