Recombinant Mouse CD74 protein (His Tag)

Product Specifications

Background

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.

Abbreviation

CD74

Synonyms

CD 74; CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex; CD74 molecule; CLIP; DHLAG; Gamma chain of class II antigens; HG2A; HLA class; class II antigen-associated) ; class II invariant chain; major histocompatibility complex

UniProt

P04441

Accession Number

P04441

Expression System

E.coli

Tag

N-His & C-His

Sequence

Gln56-Leu279

Applications

Immunogen

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.