Recombinant Mouse IFNAR1 Protein (His Tag)
Product Specifications
Background
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 . Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha-and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.
Abbreviation
IFNAR1
Synonyms
CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; IFN-R-1 IFN-alpha/beta receptor 1; IFNAR; Interferon alpha/beta receptor 1; Type I interferon receptor 1
UniProt
P33896
Accession Number
P33896-1
Expression System
E.coli
Tag
N-His
Sequence
Glu27-Cyc284
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/xh0pdk
Product MSDS
https://789.bio/eb/mDlD0C
Calculated Molecular Weight
29.4 kDa
Observed Molecular Weight
31.66 kDa
Species
Mouse
Available Sizes
Curated Selection
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