Recombinant Human UCP3 protein (SUMO, His tag)

Product Specifications

Background

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.

Abbreviation

UCP3

Synonyms

Mitochondrial uncoupling protein 3; Solute carrier family 25 member 9; UCP3

UniProt

P55916

Accession Number

P55916

Expression System

E.coli

Tag

N-SUMO-His

Sequence

Met 1-Asn 113

Field of Research

Cancer; Cardiovascular; Metabolism ; Neuroscience; signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.