Recombinant Human MAF protein (His tag)

Product Specifications

Background

C-Maf is an approximately 40 kDa transcriptional regulator that contains one bZIP domain. It can associate into homodimers and heterodimers with other basic leucine zipper transcription factors. c-Maf plays an important role in fetal erythropoiesis, lens development, mechanosensory neuron development, and the differentiation of chondrocytes and osteoblasts. In the pancreas, c-Maf promotes the transcription of glucagon in alpha cells and insulin in beta cells.

Abbreviation

MAF

Synonyms

MAF; Proto-oncogene c-Maf; Transcription factor Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog

UniProt

O75444

Accession Number

O75444-2

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Met 373

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear signaling; Immunolegy

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.