Recombinant Human MAF protein (His tag)
Product Specifications
Background
C-Maf is an approximately 40 kDa transcriptional regulator that contains one bZIP domain. It can associate into homodimers and heterodimers with other basic leucine zipper transcription factors. c-Maf plays an important role in fetal erythropoiesis, lens development, mechanosensory neuron development, and the differentiation of chondrocytes and osteoblasts. In the pancreas, c-Maf promotes the transcription of glucagon in alpha cells and insulin in beta cells.
Abbreviation
MAF
Synonyms
MAF; Proto-oncogene c-Maf; Transcription factor Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog
UniProt
O75444
Accession Number
O75444-2
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Met 373
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear signaling; Immunolegy
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
40.9 kDa
Observed Molecular Weight
45 kDa
Species
Human
Available Sizes
Documents
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