Recombinant Human GDF-15 protein (His tag)
Product Specifications
Background
Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and-9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.
Abbreviation
GDF-15
Synonyms
GDF-15; GDF15; Growth/differentiation factor 15
UniProt
Q99988
Accession Number
Q99988
Expression System
E.coli
Tag
C-His
Sequence
Gln 151-Ile 308
Field of Research
Cardiovascular; Cell Biology; signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
17.3 kDa
Observed Molecular Weight
20 kDa
Species
Human
Available Sizes
Documents
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