Recombinant Human hnRNPK protein (GST, His tag)
Product Specifications
Background
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly (C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly (C) single-stranded
Abbreviation
HnRNPK
Synonyms
HNRPK; Heterogeneous nuclear ribonucleoprotein K; Transformation up-regulated nuclear protein (TUNP)
UniProt
P61978
Accession Number
P61978-2
Expression System
E.coli
Tag
N-GST & C-His
Sequence
Met 1-Lys 219
Field of Research
Epigenetics and Nuclear signaling
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
49.0 kDa
Observed Molecular Weight
50 kDa
Species
Human
Available Sizes
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