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Recombinant Human MMP28 protein (His tag)

Product Specifications

Background

Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein that belongs to the peptidase M10A family. Matrix metalloproteinase proteins are responsible for the breakdown of the extracellular matrix which is important for normal physiological processes such as tissue remodeling, reproduction and embryonic development. Epilysin is produced by proliferating keratinocytes and is responsible for mediating the degradation of casein. Its expression is upregulated in response to injury of the skin suggesting that Epilysin may be involved in tissue repair and homeostasis.

Abbreviation

MMP28

Synonyms

Epilysin; MMP25; MMP28; Matrix metalloproteinase-28

UniProt

Q9H239

Accession Number

Q9H239-1

Expression System

E.coli

Tag

N-His & C-His

Sequence

Try131-Lys389

Field of Research

Cancer; Cell biology; Signal transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

28.4 kDa

Observed Molecular Weight

32 kDa

Species

Human

Available Sizes

Frequently Asked Questions

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