Recombinant Human NOTCH3 protein (His tag)
Product Specifications
Background
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes . The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. In both vertebrates and invertebrates, Notch signaling is important for specifying cell fates and for defining boundaries between different cell types.
Abbreviation
NOTCH3
Synonyms
NOTCH3; Neurogenic locus notch homolog protein 3
UniProt
Q9UM47
Accession Number
Q9UM47
Expression System
E.coli
Tag
N-His
Sequence
Val 1289-Cys 1458
Field of Research
Cardiovascular; Epigenetics and Nuclear signaling; Neuroscience; Stem Cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ywl4ds
Product MSDS
https://789.bio/eb/80V548
Calculated Molecular Weight
18.6 kDa
Observed Molecular Weight
20 kDa
Species
Human
Available Sizes
Curated Selection
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