Recombinant Human PPARGC1B protein (His tag)
Product Specifications
Background
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
Abbreviation
PPARGC1B
Synonyms
6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; PTPS; PTS
UniProt
Q86YN6
Accession Number
Q86YN6
Expression System
E.coli
Tag
N-His
Sequence
Leu 770-Tyr 990
Field of Research
Metabolism; Neuroscience; signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
24.2 kDa
Observed Molecular Weight
32 kDa
Species
Human
Available Sizes
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