Recombinant Human PPARGC1B protein (His tag)

Product Specifications

Background

Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

Abbreviation

PPARGC1B

Synonyms

6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; PTPS; PTS

UniProt

Q86YN6

Accession Number

Q86YN6

Expression System

E.coli

Tag

N-His

Sequence

Leu 770-Tyr 990

Field of Research

Metabolism; Neuroscience; signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.