Recombinant Human RPLP1 protein (His, GST tag)
Product Specifications
Background
RPLP1 (ribosomal protein large P1) is part of the 60S ribosomal subunit and functions in regulating elongation translation factors, and its expression is regulated by the estrogen target gene, c-Myc. RPLP1 has two alternatively spliced transcript variants that encode different proteins, with variant 1 coding for a protein of ~12-kDa molecular weight and variant 2 coding for an ~8.4-kDa protein, and the variant 1-transcribed protein appears as the major isoform. RPLP1 is proposed to play a role in diseases associated with cell proliferation and cell survival.
Abbreviation
RPLP1
Synonyms
60S acidic ribosomal protein P1; Large ribosomal subunit protein P1; RPLP1; RRP1
UniProt
P05386
Accession Number
P05386
Expression System
E.coli
Tag
N-GST & C-His
Sequence
Met 1-Asp 114
Field of Research
Epigenetics and Nuclear signaling
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/awm9dd
Product MSDS
https://789.bio/eb/l9Z5VD
Calculated Molecular Weight
37.4 kDa
Observed Molecular Weight
58 kDa
Species
Human
Available Sizes
Curated Selection
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