Recombinant Human Sperm-associated antigen 5/SPAG5 protein (His tag)
Product Specifications
Background
Astrin is a homodimeric protein with a globular head domain and a long stalk. It is an essential component of the mitotic spindle. Astrin is highly expressed in testis and is detected at low levels in placenta, liver, pancreas, thymus and colon. Its expression is cell cycle-regulated, with an increase from prophase to cytokinesis and return to basal levels at the next G1 phase. In non-dividing cells Astrin is associated with microtubules unless under cellular stress, then it is localized in stress granules.
Abbreviation
SPAG5
Synonyms
Astrin; Deepest; Mitotic spindle-associated protein p126; SPAG5; Sperm-associated antigen 5
UniProt
Q96R06
Accession Number
Q96R06
Expression System
E.coli
Tag
N-His & C-His
Sequence
Asn 482-Ala 850
Field of Research
Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
40.5 kDa
Observed Molecular Weight
48 kDa
Species
Human
Available Sizes
Frequently Asked Questions
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