Recombinant Human PRRG2 protein (GST, His tag)
Product Specifications
Background
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
PRRG2
Synonyms
PRGP2; PRRG2; Proline-rich gamma-carboxyglutamic acid protein 2; TMG2; Transmembrane gamma-carboxyglutamic acid protein 2
UniProt
O14669
Accession Number
O14669-1
Expression System
E.coli
Tag
N-GST-His
Sequence
Arg 133-His 202
Field of Research
Cardiovascular ; Cell biology ; Microbiology ; Cancer Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
32.6 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
Documents
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