Recombinant Human ATXN7L1 protein (His tag)
Product Specifications
Background
ATXN7 is found in the cytoplasm of all the populations of neurons analyzed in control brains, but nuclear labeling is observed in some neurons with a frequency and intensity weakly correlated with the topography of lesions in patients. Ataxin-7 is a component of the Tata binding protein (TBP) -free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA), which is implicated in several steps of transcriptional regulation such as histone acetylation/deubiquitinylation and recruitment of the preinitiation complex to promoters.
Abbreviation
ATXN7L1
Synonyms
ATXN7L1; Ataxin-7-like protein 1; Ataxin-7-like protein 4
UniProt
Q9ULK2
Accession Number
Q9ULK2-2
Expression System
E.coli
Tag
N-His & C-His
Sequence
Met 1- Ala 146
Field of Research
Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.0 kDa
Observed Molecular Weight
20 kDa
Species
Human
Available Sizes
Documents
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