Recombinant Human KLK3 protein (His tag)

Product Specifications

Background

KLK3 (Kallikrein 3), also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.KLK3 contains one peptidase S1 domain.KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Abbreviation

KLK3

Synonyms

APS; Gamma-Seminoprotein; Hk3; KLK2A1; Kallikrein-3; P-30 Antigen; PSA; Prostate-Specific Antigen; Semenogelase; Seminin

UniProt

P07288

Accession Number

P07288

Expression System

E.coli

Tag

N-His

Sequence

Ile 25-Pro 261

Field of Research

Signal Transduction; Tags & Cell Markers; Neuroscience; Cancer; immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.