Recombinant Human ST14/Matriptase protein (His tag)
Product Specifications
Background
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) . ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.
Abbreviation
ST14; Matriptase
Synonyms
Epithin; HAI; MTSP1; Membrane type serine protease 1; PRSS14; Prostamin; SNC19; ST14; Serine protease 14; TADG15; TMPRSS14
UniProt
Q9Y5Y6
Accession Number
Q9Y5Y6
Expression System
E.coli
Tag
N-His
Sequence
Thr 571-Val 855
Field of Research
Signal Transduction; Cancer; Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
31.2 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
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