Recombinant Human TGF-beta 2/TGFB2 protein (His tag)
Product Specifications
Background
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD) .
Abbreviation
TGF-beta 2; TGFB2
Synonyms
BSC-1 cell growth inhibitor; Cetermin; G-TSF; Glioblastoma-derived T-cell suppressor factor; Polyergin; TGF-beta-2; TGFB2; Transforming growth factor beta-2
UniProt
P61812
Accession Number
P61812
Expression System
E.coli
Tag
N-His
Sequence
Ala 303-Ser 414
Field of Research
Signal Transduction; Cell biology; Cancer; metabolism; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/g8h5xd
Product MSDS
https://789.bio/eb/hP0GRR
Calculated Molecular Weight
12.2 kDa
Observed Molecular Weight
30 kDa
Species
Human
Available Sizes
Curated Selection
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