Recombinant Human Cyclin A2/CCNA2 protein (His tag)
Product Specifications
Background
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
Abbreviation
Cyclin A2; CCNA2
Synonyms
CCN1; Cyclin-A2
UniProt
P20248
Accession Number
P20248
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Leu 432
Field of Research
Cardiovascular; Cancer; Epigenetics and Nuclear Signaling; Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
47.4 kDa
Observed Molecular Weight
55 kDa
Species
Human
Available Sizes
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