Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)

Product Specifications

Background

Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Abbreviation

IL-28B; IFN-lambda-3

Synonyms

Cytokine Zcyto; ZCYTO; IFNL3; IFN-lambda-3; IFN-lambda-4; IL-28B; IL-28C; IL28B; IL28C; Cytokine Zcyto22; IFNL4; IFN-lambda 3; interferon lambda 3; Interferon Lambda-3; Interferon Lambda-4; Interleukin-28B; Interleukin-28C; ZCYTO22

UniProt

Q8IZI9

Accession Number

Q8IZI9

Expression System

E.coli

Tag

N-His

Sequence

Val 22-Val 196

Field of Research

Signal Transduction; Microbiology; immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

19.1 kDa

Observed Molecular Weight

25 kDa

Species

Human

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ACTL9 Protein Vector (Rat) (pPM-C-His)
PV252049 500 ng

ACTL9 Protein Vector (Rat) (pPM-C-His)

Sign In for Pricing
View Details
AKT1 antibody
FNab00271 100 µg

AKT1 antibody

Sign In for Pricing
View Details
Anti-CD79b Antibody Picoband® Fluoro647 Conjugated
PB9169-Fluoro647 100 µg/Vial

Anti-CD79b Antibody Picoband® Fluoro647 Conjugated

Sign In for Pricing
View Details
Ifenprodil
YAA21058 250 mg

Ifenprodil

Sign In for Pricing
View Details
NCF4 (NM_000631) Human Tagged Lenti ORF Clone
RC216094L2 10 µg

NCF4 (NM_000631) Human Tagged Lenti ORF Clone

Sign In for Pricing
View Details
MCP3 Antibody
GWB-D19F3D 0.25 mg

MCP3 Antibody

Sign In for Pricing
View Details