Recombinant Human IL-17F protein (His tag)

Product Specifications

Background

Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

Abbreviation

IL-17F

Synonyms

Cytokine ML; Interleukin; CANDF; IL17F; CANDF6; IL-17F; ML-1; ML1; Cytokine ML-1; IL24; IL-24; Interleukin-17F; Interleukin-24

UniProt

Q96PD4

Accession Number

Q96PD4

Expression System

E.coli

Tag

C-His

Sequence

Arg 31-Gln 163

Field of Research

Cardiovascular; Cancer; immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.