Recombinant Human CXCL10 protein (His tag)
Product Specifications
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.
Abbreviation
CXCL10
Synonyms
10 kDa Interferon Gamma-Induced Protein; C-X-C Motif Chemokine 10; CXCL10; Gamma-IP10; INP10; IP-10; SCYB10; Small-Inducible Cytokine B10
UniProt
P02778
Accession Number
P02778
Expression System
E.coli
Tag
C-His
Sequence
Val 22-Pro 98
Field of Research
Cancer; immunology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
8.4 kDa
Observed Molecular Weight
12 kDa
Species
Human
Available Sizes
Documents
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