Recombinant Human CXCL10 protein (His tag)

Product Specifications

Background

Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.

Abbreviation

CXCL10

Synonyms

10 kDa Interferon Gamma-Induced Protein; C-X-C Motif Chemokine 10; CXCL10; Gamma-IP10; INP10; IP-10; SCYB10; Small-Inducible Cytokine B10

UniProt

P02778

Accession Number

P02778

Expression System

E.coli

Tag

C-His

Sequence

Val 22-Pro 98

Field of Research

Cancer; immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.