Recombinant Human CXCL14 protein (His tag)

Product Specifications

Background

Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.

Abbreviation

CXCL14

Synonyms

C-X-C Motif Chemokine 14; CXCL14; Chemokine BRAKm MIP-2G; MIP2G; NJAC; SCYB14; Small-Inducible Cytokine B14

UniProt

O95715

Accession Number

O95715

Expression System

E.coli

Tag

C-His

Sequence

Ser 35-Glu 111

Field of Research

Cancer; immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.