Recombinant Human bFGF/FGF2 protein (His tag)
Product Specifications
Background
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
Abbreviation
BFGF; FGF2
Synonyms
Basic Fibroblast Growth Factor; Bfgf; FGF-2; FGF2; FGFB; Fibroblast Growth Factor 2; HBGF-2; Heparin-Binding Growth Factor 2
UniProt
P09038
Accession Number
P09038
Expression System
E.coli
Tag
N-His
Sequence
Pro 143-Ser 288
Field of Research
Signal Transduction; Cardiovascular; Neuroscience; Cancer; Developmental Biology; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.0 kDa
Observed Molecular Weight
17 kDa
Species
Human
Available Sizes
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