Recombinant Human DES protein (His tag)
Product Specifications
Background
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
Abbreviation
DES
Synonyms
DES; Desmin; desmin
UniProt
P17661
Accession Number
P17661
Expression System
E.coli
Tag
N-His
Sequence
Ser 2-Leu 470
Field of Research
Signal Transduction; Cardiovascular; Cancer; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/mqehp5
Product MSDS
https://789.bio/eb/HC4RVL
Calculated Molecular Weight
51.5 kDa
Observed Molecular Weight
58 kDa
Species
Human
Available Sizes
Curated Selection
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