Recombinant Human PIIINP protein (His tag)
Product Specifications
Background
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Abbreviation
PIIINP
Synonyms
COL3A1; Collagen alpha-1 (III) chain; EDS4A; PIIINP
UniProt
P02461
Accession Number
P02461
Expression System
E.coli
Tag
N-His
Sequence
Gly 1059-Leu 1466
Field of Research
Signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
44.8 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
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