Recombinant Human AQP-3 protein (GST tag)
Product Specifications
Background
Water channel required to promote glycerol permeability and water transport across cell membranes.Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Abbreviation
AQP-3
Synonyms
AQP 3; AQP-3; AQP3; Aqp3; Aquaglyceroporin-3; Aquaporin 3; Aquaporin-3; Aquaporin3; GIL; Gill blood group
UniProt
Q92482
Accession Number
Q92482
Expression System
E.coli
Tag
N-GST
Sequence
Leu 110-Ser 170
Field of Research
Cancer; Metabolism; Signal transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
31.6 kDa
Observed Molecular Weight
37 kDa
Species
Human
Available Sizes
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