Recombinant Human CTSK protein (His tag)
Product Specifications
Background
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
Abbreviation
CTSK
Synonyms
CTS02; CTSK; CTSO; CTSO1; CTSO2; PKND; PYCD
UniProt
P43235
Accession Number
P43235
Expression System
E.coli
Tag
N-His
Sequence
Ala 115-Met 329
Field of Research
Cancer; Cell Biology; Cardiovascular; Neuroscience; Signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
23.5 kDa
Observed Molecular Weight
30 kDa
Species
Human
Available Sizes
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