Recombinant Human Collagen α-1 (III) Chain/COL3A1 protein (His tag)
Product Specifications
Background
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Abbreviation
Collagen α-1 Chain; COL3A1
Synonyms
CO3A1; CO3A1_HUMAN; Collagen alpha-1 (III) chain; PIIICP
UniProt
P02461
Accession Number
P02461
Expression System
E.coli
Tag
N-His
Sequence
Asp 1222-Leu 1466
Field of Research
Signal Transduction; Cell biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.8 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
Frequently Asked Questions
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