Recombinant Human Rock-2 protein (His tag)
Product Specifications
Background
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Abbreviation
Rock-2
Synonyms
ROCK 2; ROCK2; ROK alpha; ROKalpha; Rho kinase 2; Rho-associated; Rho-associated protein kinase 2; Rock II; Rock2; Rock2m
UniProt
O75116
Accession Number
O75116
Expression System
E.coli
Tag
N-His
Sequence
Leu 904-Gly 1140
Field of Research
Cancer; Cell Biology; Signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.0 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
Frequently Asked Questions
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