Recombinant Human LDHA protein (His tag)
Product Specifications
Background
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
Abbreviation
LDHA
Synonyms
Cell Proliferation-Inducing Gene 19 Protein; L-Lactate Dehydrogenase A Chain; LDH Muscle Subunit; LDH-A; LDH-M; LDHA; Renal Carcinoma Antigen NY-REN-59
UniProt
P00338
Accession Number
P00338
Expression System
E.coli
Tag
N-His
Sequence
Ala 2-Phe 332
Field of Research
Signal Transduction; Cancer; metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/dldpx5
Product MSDS
https://789.bio/eb/0dL0O0
Calculated Molecular Weight
36.3 kDa
Observed Molecular Weight
39 kDa
Species
Human
Available Sizes
Curated Selection
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