Recombinant Human DEFβ2/DEFB2 protein (GST tag)
Product Specifications
Background
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells.
Abbreviation
DEFβ2; DEFB2
Synonyms
BD-2; Beta-defensin 2; Defensin; SAP1; Skin-antimicrobial peptide 1; beta 2; hBD-2
UniProt
O15263
Accession Number
O15263
Expression System
E.coli
Tag
N-GST
Sequence
Gly24-Pro64
Field of Research
Microbiology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
30.3 kDa
Observed Molecular Weight
33 kDa
Species
Human
Available Sizes
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