Recombinant Human DEFβ2/DEFB2 protein (GST tag)

Product Specifications

Background

Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells.

Abbreviation

DEFβ2; DEFB2

Synonyms

BD-2; Beta-defensin 2; Defensin; SAP1; Skin-antimicrobial peptide 1; beta 2; hBD-2

UniProt

O15263

Accession Number

O15263

Expression System

E.coli

Tag

N-GST

Sequence

Gly24-Pro64

Field of Research

Microbiology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 85% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.