Recombinant Human PF4 protein (GST tag)
Product Specifications
Background
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Abbreviation
PF4
Synonyms
C-X-C motif chemokine 4; Endothelial cell growth inhibitor; Iroplact; Oncostatin-A; PF-4
UniProt
P02776
Accession Number
P02776
Expression System
E.coli
Tag
N-GST
Sequence
Glu32-Ser101
Field of Research
Immunology, Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
33.7 kDa
Observed Molecular Weight
34 kDa
Species
Human
Available Sizes
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