Recombinant Human GLP-1 protein (His&SUMO tag)
Product Specifications
Background
Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
Abbreviation
GLP-1
Synonyms
GLP-1; GLP-1 (7-36) ; GLP-1 (7-37) ; GLP-2; GRPP; Incretin hormone; OXM; OXY
UniProt
P01275
Accession Number
P01275
Expression System
E.coli
Tag
N-His-SUMO
Sequence
His92-Gly128
Field of Research
Signal Transduction, Stem Cells, Cancer, Developmental Biology, Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.2 kDa
Observed Molecular Weight
27 kDa
Species
Human
Available Sizes
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