Recombinant Human GLP-1 protein (His&SUMO tag)

Product Specifications

Background

Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.

Abbreviation

GLP-1

Synonyms

GLP-1; GLP-1 (7-36) ; GLP-1 (7-37) ; GLP-2; GRPP; Incretin hormone; OXM; OXY

UniProt

P01275

Accession Number

P01275

Expression System

E.coli

Tag

N-His-SUMO

Sequence

His92-Gly128

Field of Research

Signal Transduction, Stem Cells, Cancer, Developmental Biology, Metabolism

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.