Recombinant Human THP protein (His tag)
Product Specifications
Background
Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable) . May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.
Abbreviation
THP
Synonyms
Tamm-Horsfall urinary glycoprotein
UniProt
P07911
Accession Number
P07911
Expression System
E.coli
Tag
N-His
Sequence
Asp25-Phe587
Field of Research
Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
61.4 kDa
Observed Molecular Weight
50 kDa
Species
Human
Available Sizes
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