Recombinant Human MR-ProADM protein (GST tag)
Product Specifications
Background
AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Abbreviation
MR-ProADM
Synonyms
AM; PAMP; ProAM N-terminal 20 peptide; ProAM-N20
UniProt
P35318
Accession Number
P35318
Expression System
E.coli
Tag
N-GST
Sequence
Glu45-Val92
Field of Research
Neuroscience, Cardiovascular, Signal Transduction, Cancer, Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/48zqws
Product MSDS
https://789.bio/eb/5Opai9
Calculated Molecular Weight
31.3 kDa
Observed Molecular Weight
32 kDa
Species
Human
Available Sizes
Curated Selection
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