Recombinant Human FGF21 Protein
Product Specifications
Background
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression) . Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Abbreviation
FGF21
Synonyms
FGF-21; Fibroblast growth factor 21; PRO10196; UNQ3115
UniProt
Q9NSA1
Accession Number
Q9NSA1
Expression System
E.coli
Tag
N-His
Sequence
Ile 31-Ser209
Field of Research
Immunology; Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
19.2 kDa
Observed Molecular Weight
22 kDa
Species
Human
Available Sizes
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