Recombinant Human CCL22 Protein
Product Specifications
Background
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC (3-69), MDC (5-69) and MDC (7-69) seem not be active.
Abbreviation
CCL22
Synonyms
C-C motif chemokine 22; CC chemokine STCP-1; DC; MDC (1-69) ; Macrophage-derived chemokine; SCYA22; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1
UniProt
O00626
Accession Number
O00626
Expression System
E.coli
Tag
N-His
Sequence
Gly25-Gln93
Field of Research
Immunology; Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ccok4c
Product MSDS
https://789.bio/eb/xD4tLR
Calculated Molecular Weight
10.4 kDa
Observed Molecular Weight
10 kDa
Species
Human
Available Sizes
Curated Selection
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