Recombinant Human GRO Protein

Product Specifications

Background

Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha (4-73), GRO-alpha (5-73) and GRO-alpha (6-73) show a 30-fold higher chemotactic activity.

Abbreviation

GRO

Synonyms

C-X-C motif chemokine 1; CXCL1; GRO-alpha (1-73) ; GRO1; GROA; Growth-regulated alpha protein; MGSA; Melanoma growth stimulatory activity; NAP-3; Neutrophil-activating protein 3; SCYB1

UniProt

P09341

Accession Number

P09341

Expression System

E.coli

Tag

N-His

Sequence

Ala35-Asn107

Field of Research

Cancer; Cardiovascular; Immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.