Recombinant Human IL-4 Protein

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Interleukin; B-cell growth factor; BSF; IL4; BCGF-1; BCGF1; BSF-1; BSF1; IL-4; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; Binetrakin; IGG1 induction factor; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.