Recombinant Human IL6R protein (His Tag)
Product Specifications
Background
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Abbreviation
IL6R
Synonyms
Membrane glycoprotein; CD126; gp80; IL6Q; IL-6R; IL-6R 1; IL-6R subunit alpha; IL-6R-1; IL6RA; IL-6RA; IL-6R-Alpha; IL6RQ; Interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; IL6R; IL-6Rα alpha; CD 126; CD126 antigen; IL 6R; IL 6R 1; IL 6R alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R 1 Membrane glycoprotein 80 (gp80) ; Interleukin 6 receptor; MGC30256
UniProt
P08887
Accession Number
P08887
Expression System
E.coli
Tag
N-His
Sequence
Leu20-Pro365
Applications
Immunogen
Field of Research
Immunology; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
39.9 kDa
Observed Molecular Weight
38-40 kDa
Species
Human
Available Sizes
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