Recombinant Human CD59 glycoprotein protein (His Tag)
Product Specifications
Background
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Abbreviation
CD59
Synonyms
16.3A5;1F5; EJ16; EJ30; EL32; FLJ38134; FLJ92039; G344; HRF 20; Ly 6
UniProt
P13987
Accession Number
P13987-1
Expression System
E.coli
Tag
N-His
Sequence
Leu26-Asn102
Applications
Immunogen
Field of Research
Immunology, Signal Transduction, Stem Cells, Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
10.2 kDa
Observed Molecular Weight
14-16 kDa
Species
Human
Available Sizes
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