Recombinant Human CD59 glycoprotein protein (His Tag)

Product Specifications

Background

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Abbreviation

CD59

Synonyms

16.3A5;1F5; EJ16; EJ30; EL32; FLJ38134; FLJ92039; G344; HRF 20; Ly 6

UniProt

P13987

Accession Number

P13987-1

Expression System

E.coli

Tag

N-His

Sequence

Leu26-Asn102

Applications

Immunogen

Field of Research

Immunology, Signal Transduction, Stem Cells, Cardiovascular

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.