Recombinant Human KRT7 Protein (His Tag)
Product Specifications
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.
Abbreviation
KRT7
Synonyms
55K type II cytoskeletal; CK 7; CK-7; CK7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K7; Kerat; Keratin; Keratin 7; Keratin type II cytoskeletal 7; simple epithelial; simple epithelial type I; type II; type II cytoskeletal 7
UniProt
P08729
Accession Number
P08729-1
Expression System
E.coli
Tag
N-His
Sequence
Glu91-Asp469
Field of Research
Signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/aaidlp
Product MSDS
https://789.bio/eb/aHRRlL
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
44.3 kDa
Species
Human
Available Sizes
Curated Selection
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