Recombinant Human FABP2/I-FABP Protein (His Tag)

Product Specifications

Background

Fatty Acid-Binding Protein 2 (FABP2) is a cytoplasm protein that belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP2 is expressed in the small intestine and at much lower levels in the large intestine, the highest expression levels in the jejunum. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis and may also help maintain energy homeostasis by functioning as a lipid sensor.

Abbreviation

FABP2; I-FABP

Synonyms

FABP2; FABPI; Fatty Acid-Binding Protein 2; Fatty Acid-Binding Protein Intestinal; I-FABP; Intestinal-Type Fatty Acid-Binding Protein

UniProt

P12104

Accession Number

P12104

Expression System

E.coli

Tag

N-His & C-His

Sequence

Met1-Asp132

Field of Research

Signal Transduction; Cardiovascular; Cancer; Developmental Biology; metabolism; Stem cells

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.